Comments on: Not-so-whole Exome Sequencing http://massgenomics.org/2010/06/not-so-whole-exome-sequencing.html Medical genomics in the post-genome era Fri, 27 Apr 2012 18:07:26 +0000 hourly 1 http://wordpress.org/?v=3.3.1 By: German Leparc http://massgenomics.org/2010/06/not-so-whole-exome-sequencing.html/comment-page-1#comment-401 German Leparc Fri, 06 Aug 2010 13:18:44 +0000 http://www.massgenomics.org/?p=725#comment-401 What I actually found most interesting is the PCR duplicates and how they significantly dropped when using paired-end reads vs single ends. This means that a lot of people who have been filtering our PCR duplicates on single ends reads have been throwing away a significant amount of data! What I actually found most interesting is the PCR duplicates and how they significantly dropped when using paired-end reads vs single ends. This means that a lot of people who have been filtering our PCR duplicates on single ends reads have been throwing away a significant amount of data!

]]> By: cheese http://massgenomics.org/2010/06/not-so-whole-exome-sequencing.html/comment-page-1#comment-396 cheese Fri, 09 Jul 2010 22:48:15 +0000 http://www.massgenomics.org/?p=725#comment-396 unfortunately, not apples to apples, but i think it shows the power of paired reads more than a system comparison. fragment vs paired.... both platforms can do paired reads for SNP calling, but i agree illumina has the advantage in the exome market. unfortunately, not apples to apples, but i think it shows the power of paired reads more than a system comparison. fragment vs paired….

both platforms can do paired reads for SNP calling, but i agree illumina has the advantage in the exome market.

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