Comments on: Next-Gen Sequencing in 2010

By: Pathogens: Genes and Genomes » 3rd-generation Sequencing: A RISC-y Business

Pathogens: Genes and Genomes » 3rd-generation Sequencing: A RISC-y Business — Tue, 18 May 2010 16:13:55 +0000

[...] earlier in the year. Most of this was already known thanks to the reporting from bloggers like Dan Koboldt, Luke Jostins and Daniel Macarthur at the time, but the Nature article is sure to bring [...]

By: Personalized Genomics: Genetic Testing Registry and Next-Gen Sequencing « ScienceRoll

Wed, 24 Mar 2010 01:11:48 +0000

[...] Next-Gen Sequencing in 2010 (Mass Genomics): Everything you need to know about next-generation sequencing. [...]

By: Why the State of Personal Genomics is Not as Dire as You Think

Why the State of Personal Genomics is Not as Dire as You Think — Thu, 11 Mar 2010 23:04:19 +0000

[...] the field of personal genomics, an industry-wide trend that is not dissimilar from that which is occurring in the genomic sequencing field. (The segmentation of personal genomics will be one topic of conversation at the upcoming GET [...]

By: DNA Sequencing Companies

DNA Sequencing Companies — Thu, 11 Mar 2010 00:54:20 +0000

[...] – To read some good analysis on DNA sequencing companies, check out: – Dan Koboldt on the Fragmentation of Sequencing Market – My previous post which summarizes analysis from the AGBT [...]

By: sm

sm — Wed, 10 Mar 2010 19:11:51 +0000

Thanks Dan. Indeed thats exciting. Ion torrent is the one I am most curious about.

By: eric antoniou

eric antoniou — Wed, 10 Mar 2010 18:51:04 +0000

I am wondering how much of the shift from “taking over the world” to “niche market” is driven by financial constraints. In 2009, many of the new companies on the market were raising money from investors, and it helps to make large claims when you do that. This year, these companies have now, or are close to have, instruments (or service for Complete Genomics) for sale and they are focusing on showing to their investors that they can generate sales.

By: Daniel MacArthur

Daniel MacArthur — Wed, 10 Mar 2010 11:05:23 +0000

Great post, Dan.

Regarding the QDot, it’s worth noting that the presenter claimed that beta machines would be shipped to early access customers by the end of the year. Assuming that this claim has any validity – and I admit that’s a big if – we might see a commercial release some time in 2010.

By: Dan Koboldt

Dan Koboldt — Tue, 09 Mar 2010 20:09:56 +0000

Jamie,

Good question – I think that people at AGBT were impressed by the QDot presentation (and the speaker, Joseph Beecham). However, given that only movies were shown, this technology seems years away from market entry.

By: Jamie Taylor

Jamie Taylor — Tue, 09 Mar 2010 19:08:31 +0000

Great post. Question regarding Life Technologies: why did you exclude their QDot / FRET based sequencing (http://tinyurl.com/ycfa9kw) from your Single Molecule Sequencing applications? It’s my understanding that people were pretty excited about their platform at AGBT (unfortunately I couldn’t make it).